I think I remember reading somewhere that if the speaker is really underpowered (40W vs 225W) it might not sound very good. Won't hurt to try it though, and if it does sound good then you're set!

__________________
Fender Strat
Fender Blacktop Tele
TB FX Loop/Channel Switcher > (in loop) > Mojo Hand Analog Filter > EQD Dream Crusher Fuzz > Subdecay Liquid Sunshine > Frazz Dazzler > Line 6 M9 > EHX Memory Toy > (end of loop)
Soldano HR50+

Rig Thread